We study protein homeostasis in healthy and malignant haematopoietic stem cells, from the earliest steps of blood formation to transformation in acute myeloid leukaemia.
Proteostasis in stem cells, AML leukaemic stem cells and drug resistance, HSC expansion and transplantation, and multimodal approaches to stem cell biology.
See the programme → 02 / DatasetsMulti-omic datasets, with links to code repositories and interactive R/Shiny browsers.
Browse datasets → 03 / PublicationsPeer-reviewed papers and preprints from the lab and our collaborators.
Read publications →Quantitative proteomics, high-parameter flow cytometry and in vivo and ex vivo haematopoietic models, with established clinical partnerships with Leeds St James Hospital and the Anthony Nolan Trust.
How to work with us →